DeSimone Functional Medicine

DeSimone Functional Medicine

Empowering you on your path to health

Skip to content
  • Home
  • About
    • Our Philosophy
    • Meet Us
    • FAQs
    • Benefits
  • What We Provide
    • Services
    • Why Functional Medicine?
    • Reviews
    • Letter to My Patients
  • Become a Patient
  • Blog
  • Contact
  • (973) 886-2195

Two offices, one membership

by Robert DeSimone on September 1, 2026

I practice in Florham Park and in Bonita Springs. Same physician. Same membership. New Jersey: 254 Columbia Tpke, Unit 200, Florham Park. Morris, Somerset, Bergen. Florida: 24860 Burnt Pine Drive, […]

Read more →

Same 10% weight loss. The liver still saw a diet effect.

by Robert DeSimone on September 1, 2026

Same 10% down on three diets. Muscle insulin sensitivity rose about 50% on keto, Mediterranean, and very-low-fat. Liver fat and hepatic insulin sensitivity did not. Petersen, Klein, and colleagues at […]

Read more →

Coffee is not a caffeine delivery system

by Robert DeSimone on August 31, 2026

Most people treat coffee as a stimulant with a side of habit. A 2026 open-access review in the Journal of Translational Medicine is more interesting, and more cautious, than that. […]

Read more →

Your heart and your skeletal muscle age on the same clock

by Robert DeSimone on August 26, 2026

Your biceps and your left ventricle are not separate projects. A December 2025 state-of-the-art review in JACC Advances maps the shared biology of skeletal muscle aging (sarcopenia) and cardiac muscle […]

Read more →

When the brain can’t run on sugar, can fasting help it switch fuels?

by Robert DeSimone on August 23, 2026

Alzheimer’s is not only plaques and tangles. One of the earliest problems is that the brain stops using glucose well. A 2026 review asks whether intermittent fasting can help it switch fuels.

Read more →

Responsiveness of epigenetic aging biomarkers

by Robert DeSimone on August 22, 2026

A new study shows how the epigenetic aging clocks respond to interventions that promote longevity. The paper looks at whether epigenetic clocks actually move when you try to slow aging. […]

Read more →

Coffee, Caffeine & Your Heart: What Does the Latest AHA Statement Say?

by Robert DeSimone on July 24, 2026

Good news for coffee lovers! The American Heart Association (AHA) released a comprehensive Scientific Statement on caffeine and cardiovascular disease. Here is what the latest science shows about your daily […]

Read more →

Turning Back the Clock on Protein Damage!

by Robert DeSimone on July 24, 2026

Can we reverse molecular aging? For years, scientists believed that certain age-related protein damage was permanent. A groundbreaking new study published in Nature Communications suggests we might finally be able […]

Read more →

New research in Nature Genetics just dropped the most detailed map ever of how our “biological clocks”—leukocyte telomere length (LTL)—vary across the US!

by Robert DeSimone on March 28, 2026

New research in Nature Genetics just dropped the most detailed map ever of how our “biological clocks”—leukocyte telomere length (LTL)—vary across the US! https://doi.org/10.1038/s41588-026-02567-1 Geography Matters: Significantly longer telomeres were […]

Read more →

Can a Ketogenic Diet Lower Lipoprotein(a)?

by Robert DeSimone on March 19, 2026

Lipoprotein(a), or Lp(a), has long been considered a “genetically determined” cardiovascular risk factor that remains stable throughout a person’s life. However, a striking new $n=1$ study published in BMJ Nutrition, […]

Read more →

Post navigation

← Older posts

Recent Posts

  • Two offices, one membership
  • Same 10% weight loss. The liver still saw a diet effect.
  • Coffee is not a caffeine delivery system
  • Your heart and your skeletal muscle age on the same clock
  • When the brain can’t run on sugar, can fasting help it switch fuels?

DeSimone Functional Medicine

Florida Office

24860 Burnt Pine Drive, Ste 1 & 2

Bonita Springs, FL 34134

(973) 886.2195

DrRob@DeSimoneFM.com

Serving

Estero • North Naples

Bonita Springs

Fort Myers • Etc.

New Jersey Office

254 Columbia Tpke, Unit 200

Florham Park, NJ 07932

(973) 886.2195

DrRob@DeSimoneFM.com

Serving

Morris County

Somerset County

Bergen County

Florida Office

24860 Burnt Pine Drive, Ste 1 & 2

Bonita Springs, FL 34134

(973) 886.2195

DrRob@DeSimoneFM.com

New Jersey Office

254 Columbia Tpke, Unit 200

Florham Park, NJ 07932

(973) 886.2195

DrRob@DeSimoneFM.com

Serving

Estero • North Naples

Bonita Springs

Fort Myers • Etc.

Serving

Morris County

Somerset County

Bergen County

Information Policy | Notice of Privacy Practices

Copyright © 2026 DeSimone Functional Medicine | All Rights Reserved.

Consultant: Latady Physician Strategies, LLC | Designer: Rotate Graphics | Developer: OpenMode LLC